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Artificial ovary may boost fertility and postpone the menopause

Making a synthetic home for a woman's egg-producing follicles could improve fertility after chemotherapy and help women with endometriosis conceive, reports New Scientist magazine.

Science & Technology, Women's Health

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A SYNTHETIC ovary that could help both older women and those with endometriosis conceive is a step closer. Initially intended for women who have undergone cancer treatment, the prototype is the first artificial organ capable of keeping human egg-producing follicles alive outside a woman’s body. It may also be used to delay the onset of the menopause.

Women can become infertile after cancer treatment as the ovaries and the egg-making follicles they contain are vulnerable to chemotherapy, especially for leukaemias, brain cancers and lymphomas. Removing and freezing ovarian tissue beforehand to reimplant after treatment can help women conceive, but there is a risk that this tissue will reintroduce hidden cancer cells.

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When the team implanted two of these synthetic ovaries into each of the abdominal cavities of eight mice, more than a fifth of the follicles were still alive a week later (To read complete article, please Subscribe to the New Scientist Magazine. Now available in Pakistan)

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